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Mouse Parvovirus (MPV)

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Etiology

  • family Parvoviridae
    • genus Parvovirus

Clinical signs & Epizootiology

  • ์ฆ์ƒ : silent
  • ๋งˆ์šฐ์Šค ์ž์—ฐ ๊ฐ์—ผ (MVM๋ณด๋‹ค ํ”ํ•จ)
  • infant, adult mice์—์„œ ์ง€์†๊ฐ์—ผ. (MVM์€ ์ง€์†๊ฐ์—ผ X)
  • ์†Œ์žฅ์— ๊ฐ์—ผ, ๋ถ„๋ณ€์„ ํ†ตํ•ด ๋ฐ”์ด๋Ÿฌ์Šค ๋ฐฐ์ถœ

Pathology

  • ์กฐ์ง๋ณ‘๋ฆฌํ•™์  ์†Œ๊ฒฌ ์—†์Œ
  • ์žฅ์ ๋ง‰์—์„œ ๋ณต์ œ๋œ ํ›„, lung, kidney, liver, ๋ฆผํ”„ ์žฅ๊ธฐ๋กœ ์ด๋™
  • lymphocytotropism : lymphocyte ๊ฐ์—ผ. ๊ธ‰์„ฑ ๊ฐ์—ผ ๋™์•ˆ ๋ฐ”์ด๋Ÿฌ์Šค๊ฐ€ lymph node์— ํผ์ ธ ์žˆ๋‹ค๊ฐ€, ์ง€์†๊ฐ์—ผ๋˜๋ฉด germinal center๋กœ ์ด๋™
    (์†Œ์žฅ์˜ villi. ๊ฒ€์ • particle์ด virus particle)

Graph View

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