19. Filoviridae

Keyword

• filament 모양, intracytoplasmic inclusion body

type	ssRNA
genome	1 (-) linear
morphology	filamentous
envelope	O
복제효소 / 장소	virion RNA polymerase / 세포질

Classification

• Order Mononegavirales : Paramyxoviridae , Rhabdoviridae, Bornaviridae 등 속함 (복제방식 유사)
  • family Filoviridae
    • genus Marburgvirus
    • genus Ebolavirus

Structure

• (-) ssRNA
• pleomorphic(다형성), 길이가 긴 filament 형상.
  • 균일한 80nm 직경에 길이가 제각각 (Marburg 800nm, Ebola 1000nm)
• 나선형 nucleocapsid + spike 포함 envelope
• intracytoplasmic inclusion body 형성