Cell Adaptation

  • ์ฃฝ์ง€ ์•Š์„ ์ •๋„์˜ ์†์ƒ์ด ๊ฐ€ํ•ด์ง€๋ฉด cell์€ ์—ฌ๋Ÿฌ ๋ฐฉ์‹์œผ๋กœ โ€˜์ ์‘โ€™ํ•œ๋‹ค.

  • hypertrophy : cell size ์ปค์ง

  • hyperplasia : cell number ์ฆ๊ฐ€

  • metaplasia : cell type ๋ณ€ํ™”

  • dysplasia : ๋น„์ •์ƒ์  ๋ชจ์–‘

ํ‡ดํ–‰์„ฑ ๋ณ€ํ™”

  • atrophy : ์œ„์ถ•. cell size ๊ฐ์†Œ

  • accumulation : normal/abnormal substance ์ถ•์ 

  • autophagy : ์„ธํฌ๊ฐ€ ํ‡ดํ™”ํ•˜๊ฑฐ๋‚˜ ischemia ํ•˜๋Š” ์ค‘, growth factor๋‚˜ hormonal stimuli๊ฐ€ ์—†์–ด์ง์— ๋”ฐ๋ผ ์„ธํฌ๊ฐ€ ์ƒ์กดํ•˜๋Š” mechanism

  • ์ž๊ธฐ โ€˜์Šค์Šค๋กœโ€™ ๋ฌธ์ œ๊ฐ€ ์žˆ๋Š” organelles, proteins ๋“ฑ์„ ์†Œํ™”ํ•œ๋‹ค.

  • heterophagy์™€๋Š” ๋‹ค๋ฆ„

  • cell death๋ฅผ ์œ ๋ฐœ

  • macroautophagy, microautophagy, chaperone-assisted autophagy๋กœ ๋ถ„๋ฅ˜ํ•จ