공보2(A) - 11. Picornaviridae

• family Picronaviridae
  • genus Rhinovirus
  • genus Enterovirus : swine vesicular disease virus
  • genus Aphthovirus
    • FMD : foot-and-mouth diseases virus
  • genus Cardiovirus
  • genus Hepatovirus : hepatitis A
  • genus Parechovirus

Aphthovirus

Foot-and-Mouth Disease

• Etiology : FMD virus (7 serotypes)
• Occurence
  • higly contagious virus, exclusively cloven-hooved animals
  • worldwide / except Australia, New Zealand, North America
• Transmission
  • contact, vectors(human, birds, rodents 등), aerosol, contaminated water
  • human infection : direct handling of infected animals, contact during slaughter aerosol은 틀림
  • muscle tissues of cadavers(사체의 근육 조직)에서는 virus not found (pH 5.3 이하에서 rapidly inactivated)
• Clinical manifestation
  • skin lesion : heal in 5-10 days
  • involvement of CNS X
  • mortality는 높지 않음
• vesicle을 형성하는 다른 감염성 질병 : Herpesvirus, Vesicular stomatitis"비슷한 증상"으로 출제, Hand foot and mouth disease
  • Hand foot and mouth disease : FMD가 아니라, enterovirus A(coxsackievirus A16), 사람에서 FMD보다 더 common