Zika virus

• human birth defects : 소두증(microcephaly)의 원인
• Etiology
• Occurence
  • 열대지방 : infants born with microcephaly 발생
  • 국내에서 소수 발생, 소두증은 발생X
• Transmission
  • Mosquito-borne Transmission
  • Nonmosquito Transmission
    • mother to fetus during pregnancy (수직전파)
    • sexual/blood transmission
• Clinical manifestation
  • Acute febrile illness : 주로 rash, fever, arthritis
  • Neurologic complications : Guillain-Barré syndrome
  • Adverse fetal outcomes : 소두증(microcephaly)
• Therapy & Prophylaxis
  • no therapy (대증치료)
  • no vaccine
  • prevention, control이 중요